Bloodshots are zombies that have been severely warped by the C-virus. Their skin has completely dissolved, exposing all of their muscle tissue and altering the position of several bones. The head no longer looks human; the ears and nose have shriveled and the eyes have melted away, the mouth consisting of rows of individually-wriggling jagged fangs.

Bloodshots are much more ferocious than standard zombies and much stronger, capable of taking gunshots without even flinching. They attack by pouncing upon human prey and tearing out the victim's throat. Unlike other zombies, the Bloodshot's weakness isn't its head. Its heart expands as a result of its mutation and occasionally pushes through its ribcage and out of the chest. Any strike to this area is enough to kill the creature.

Additionally, Bloodshots are severely weak against fire and zombies who can turn into Bloodshots can be recognised by a distinct redness of the skin and eyes.

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